F2552
Sigma
Formestane
solid
| Synonym: | 4-Hydroxyandrost-4-ene-3,17-dione, CGP-32349 |
| CAS Number: | 566-48-3 |
| Linear Formula: | C19H26O3 |
| Molecular Weight: | 302.41 |
| MDL number: | MFCD00057814 |
| PubChem Substance ID: | 24894827 |
Description
| Biochem/physiol Actions | Aromatase inhibitor used as an anti-cancer agent against estrogen-dependent tumors. |
Properties
| form | solid |
| Gene Information | human ... CYP19A1(1588) |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 60 |
| Safety Statements | 53-36/37/39-45 |
| WGK Germany | 3 |
| RTECS | BV8152500 |
References
| reference | Lonning, P. E., et al., Pharmacokinetics and metabolism of formestane in breast cancer patients. J. Steroid Biochem. 77, 39, (2001) |
| Brodie, A. M., Njar, V. C., Aromatase inhibitors and their application in breast cancer treatment. Steroids 65, 171, (2000) Abstract |
